X-ray diffraction
2.6Å resolution

Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Solute carrier family 2, facilitated glucose transporter member 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 518 amino acids
Theoretical weight: 56.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P11169 (Residues: 1-496; Coverage: 100%)
Gene names: GLUT3, SLC2A3
Sequence domains: Sugar (and other) transporter
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: P21
Unit cell:
a: 78.109Å b: 121.88Å c: 96.078Å
α: 90° β: 108.14° γ: 90°
R R work R free
0.217 0.215 0.251
Expression system: Spodoptera frugiperda