X-ray diffraction
1.5Å resolution

Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5 angstrom


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Solute carrier family 2, facilitated glucose transporter member 3 Chain: A
Molecule details ›
Chain: A
Length: 518 amino acids
Theoretical weight: 56.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P11169 (Residues: 1-496; Coverage: 100%)
Gene names: GLUT3, SLC2A3
Sequence domains: Sugar (and other) transporter
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: P21
Unit cell:
a: 48.338Å b: 118.132Å c: 51.341Å
α: 90° β: 102.67° γ: 90°
R R work R free
0.184 0.184 0.199
Expression system: Spodoptera frugiperda