4ztx

X-ray diffraction
2.1Å resolution

Neurospora crassa cobalamin-independent methionine synthase complexed with Zn2+

Released:
Source organism: Neurospora crassa

Function and Biology Details

Reaction catalysed:
5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Chain: A
Molecule details ›
Chain: A
Length: 769 amino acids
Theoretical weight: 86.43 KDa
Source organism: Neurospora crassa
UniProt:
  • Canonical: Q8X1E4 (Residues: 1-769; Coverage: 100%)
Gene names: GE21DRAFT_4142, met-8
Sequence domains:
Structure domains: TIM Barrel

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 78.254Å b: 94.63Å c: 114.907Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.163 0.217