4ztg

X-ray diffraction
2.8Å resolution

Ebola virus nucleoprotein bound to VP35 chaperoning peptide P22121

Released:
Entry authors: Kirchdoerfer RN, Abelson DM, Saphire EO

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein; Polymerase cofactor VP35 Chain: A
Molecule details ›
Chain: A
Length: 381 amino acids
Theoretical weight: 42.31 KDa
Source organism: Ebola virus - Mayinga, Zaire, 1976
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05127 (Residues: 15-60; Coverage: 14%)
  • Canonical: P18272 (Residues: 34-367; Coverage: 45%)
Gene names: NP, VP35

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Unit cell:
a: 33.349Å b: 92.398Å c: 133.626Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.262 0.259 0.293
Expression system: Escherichia coli