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X-ray diffraction
2.48Å resolution

MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 7 Chain: A
Molecule details ›
Chain: A
Length: 344 amino acids
Theoretical weight: 39.41 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q13164 (Residues: 50-393; Coverage: 42%)
Gene names: BMK1, ERK5, MAPK7, PRKM7
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P41212
Unit cell:
a: 93.04Å b: 93.04Å c: 110.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.167 0.23
Expression system: Spodoptera frugiperda