PDBe 4zom

X-ray diffraction
2.27Å resolution

RORgamma in complex with inverse agonist 4j.


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Nuclear receptor ROR-gamma Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 225 amino acids
Theoretical weight: 26.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P51449 (Residues: 265-487; Coverage: 43%)
Gene names: NR1F3, RORC, RORG, RZRG
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P31
Unit cell:
a: 99.422Å b: 99.422Å c: 129.439Å
α: 90° β: 90° γ: 120°
R R work R free
0.202 0.2 0.24
Expression system: Escherichia coli BL21(DE3)