4zne

X-ray diffraction
2.42Å resolution

IgG1 Fc-FcgammaRI ecd complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
High affinity immunoglobulin gamma Fc receptor I Chain: A
Molecule details ›
Chain: A
Length: 267 amino acids
Theoretical weight: 30 KDa
Source organism: Homo sapiens
Expression system: Mammalian expression vector pCK146
UniProt:
  • Canonical: P12314 (Residues: 16-282; Coverage: 74%)
Gene names: FCG1, FCGR1, FCGR1A, IGFR1
Sequence domains:
Structure domains: Immunoglobulins
Immunoglobulin heavy constant gamma 1 Chains: E, J
Molecule details ›
Chains: E, J
Length: 227 amino acids
Theoretical weight: 25.58 KDa
Source organism: Homo sapiens
Expression system: Mammalian expression vector pBGSA
UniProt:
  • Canonical: P01857 (Residues: 104-330; Coverage: 69%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 134.735Å b: 126.75Å c: 71.844Å
α: 90° β: 118.44° γ: 90°
R-values:
R R work R free
0.203 0.201 0.254
Expression systems:
  • Mammalian expression vector pCK146
  • Mammalian expression vector pBGSA