› 4zn2

X-ray diffraction
2Å resolution

Glycosyl hydrolase from Pseudomonas aeruginosa

Released:
DOI: 10.2210/pdb4zn2/pdb
PDB entry 4zn2 coloured by chain, front view.
PDB entry 4zn2 coloured by chain, side view.
PDB entry 4zn2 coloured by chain, top view.
Source organism: Pseudomonas aeruginosa PAO1
Primary publication:
PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix.
Yu S, Su T, Wu H, Liu S, Wang D, Zhao T, Jin Z, Du W, Zhu MJ, Chua SL, Yang L, Zhu D, Gu L, Ma LZ
Cell Res 25 1352-67 (2015)
PMID: 26611635

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191272 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PslG Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 416 amino acids
Theoretical weight: 47.27 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9I1N2 (Residues: 31-442; Coverage: 93%)
Gene names: PA2237, pslG

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 55.559Å b: 88.206Å c: 222.394Å
α: 90° β: 96.92° γ: 90°
R-values:
R R work R free
0.195 0.193 0.224
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

21 review citations

Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action.
Roy et al. (2018)
20 more

3 mentions without citation

PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix.
Yu et al. (2015)
2 more