4zk0

X-ray diffraction
2.15Å resolution

Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin B3 Chain: A
Molecule details ›
Chain: A
Length: 390 amino acids
Theoretical weight: 44.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29508 (Residues: 1-390; Coverage: 100%)
Gene names: SCCA, SCCA1, SERPINB3
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P212121
Unit cell:
a: 50.808Å b: 68.273Å c: 105.773Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.174 0.234
Expression system: Escherichia coli BL21(DE3)