› 4zhi

X-ray diffraction
2.3Å resolution

Eg5 motor domain mutant E162S

Released:
DOI: 10.2210/pdb4zhi/pdb
PDB entry 4zhi coloured by chain, front view.
PDB entry 4zhi coloured by chain, side view.
PDB entry 4zhi coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Luo M, Park C, Worthylake D, Kim S

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156612 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF11 Chains: A, B
Molecule details ›
Chains: A, B
Length: 369 amino acids
Theoretical weight: 41.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P52732 (Residues: 1-369; Coverage: 35%)
Gene names: EG5, KIF11, KNSL1, TRIP5
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

1 bound ligand:
Ligand ADP 2 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P21
Unit cell:
a: 52.72Å b: 81.22Å c: 82.6Å
α: 90° β: 94.31° γ: 90°
R-values:
R R work R free
0.254 0.254 0.304
Expression system: Escherichia coli BL21(DE3)

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