› 4zei

X-ray diffraction
2.3Å resolution

PBP AccA from A. tumefaciens C58 in complex with L-arabinose-2-phosphate

Released:
DOI: 10.2210/pdb4zei/pdb
PDB 4zei coloured by chain and viewed from the front.
PDB 4zei coloured by chain and viewed from the side.
PDB 4zei coloured by chain and viewed from the top.
Source organism: Agrobacterium fabrum str. C58
Primary publication:
A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens.
El Sahili A, Li SZ, Lang J, Virus C, Planamente S, Ahmar M, Guimaraes BG, Aumont-Nicaise M, Vigouroux A, Soulère L, Reader J, Queneau Y, Faure D, Moréra S
PLoS Pathog 11 e1005071 (2015)
PMID: 26244338

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute-binding protein family 5 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 499 amino acids
Theoretical weight: 57.18 KDa
Source organism: Agrobacterium fabrum str. C58
Expression system: Escherichia coli
UniProt:
  • Canonical: Q52012 (Residues: 30-521; Coverage: 99%)
Gene names: Atu6139, accA
Sequence domains: Bacterial extracellular solute-binding proteins, family 5 Middle
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand LAO 1 x LAO
Ligand EDO 5 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2221
Unit cell:
a: 77.97Å b: 114.86Å c: 109.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.197 0.249
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Natural Trojan horse inhibitors of aminoacyl-tRNA synthetases.
Travin et al. (2021)
3 more

1 mention without citation

A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens.
El Sahili et al. (2015)