› 4zdh

X-ray diffraction
2.1Å resolution

Crystal structure of JKA6 TCR

Released:
DOI: 10.2210/pdb4zdh/pdb
PDB entry 4zdh coloured by chain, front view.
PDB entry 4zdh coloured by chain, side view.
PDB entry 4zdh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Singh NK, Hossain M, Baker BM

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-100462 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T cell receptor alpha chain constant; T cell receptor alpha variable 12-2 Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 22.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A0A075B6T6 (Residues: 24-112; Coverage: 96%)
  • Canonical: P01848 (Residues: 1-91; Coverage: 65%)
Gene names: TCRA, TRAC, TRAV12-2
Sequence domains:
Structure domains: Immunoglobulins
T cell receptor beta constant 1; T cell receptor beta variable 28 Chain: B
Molecule details ›
Chain: B
Length: 241 amino acids
Theoretical weight: 27.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A0A5B6 (Residues: 22-113; Coverage: 99%)
  • Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Gene names: TCRBV3S1, TRBC1, TRBV28
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 44.695Å b: 60.087Å c: 82.462Å
α: 90° β: 91.75° γ: 90°
R-values:
R R work R free
0.192 0.19 0.224
Expression system: Escherichia coli BL21

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