› 4zbm

X-ray diffraction
1.9Å resolution

Crystal structure of Drosophila cyclic nucleotide gated channel pore mimicking NaK mutant

Released:
DOI: 10.2210/pdb4zbm/pdb
PDB 4zbm coloured by chain and viewed from the front.
PDB 4zbm coloured by chain and viewed from the side.
PDB 4zbm coloured by chain and viewed from the top.
Source organism: Bacillus cereus ATCC 14579
Primary publication:
Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels.
Lam YL, Zeng W, Derebe MG, Jiang Y
OpenAccess logo J Gen Physiol 146 255-63 (2015)
PMID: 26283200

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ion_trans_2 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 97 amino acids
Theoretical weight: 10.69 KDa
Source organism: Bacillus cereus ATCC 14579
Expression system: Escherichia coli
UniProt:
  • Canonical: Q81HW2 (Residues: 20-110; Coverage: 79%)
Gene name: BC_0669
Sequence domains: Ion channel
Structure domains: Helix Hairpins

Ligands and Environments

2 bound ligands:
Ligand K 5 x K
Ligand BA 2 x BA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: I4
Unit cell:
a: 67.907Å b: 67.907Å c: 89.799Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.236
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.
Dhakshnamoorthy et al. (2016)