PDBe 4z54

X-ray diffraction
1.83Å resolution

High Resolution Human Septin3 GTPase domain with alpha-zero helix in complex with GDP

Source organism: Homo sapiens
Entry authors: Valadares NF, Macedo JN, Pereira HM, Brandao-Neto J, Matos SO, Leonardo DA, Araujo APU, Garratt RC

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Neuronal-specific septin-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 287 amino acids
Theoretical weight: 33.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9UH03 (Residues: 43-329; Coverage: 80%)
Gene names: SEP3, SEPT3, SEPTIN3

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P1
Unit cell:
a: 43.41Å b: 44.55Å c: 78.95Å
α: 99.29° β: 100.77° γ: 108.39°
R R work R free
0.171 0.17 0.199
Expression system: Escherichia coli BL21(DE3)