4yxh

X-ray diffraction
2.7Å resolution

Crystal structure of Deer prion protein complexed with POM1 FAB

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric
hetero dimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.96 KDa
Source organism: Odocoileus hemionus
Expression system: Escherichia coli
UniProt:
  • Canonical: P47852 (Residues: 124-231; Coverage: 47%)
Gene names: PRNP, PRP
POM1 FAB HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 218 amino acids
Theoretical weight: 23.4 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
POM1 FAB LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 23.51 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: C2
Unit cell:
a: 84.282Å b: 106.58Å c: 75.775Å
α: 90° β: 95.81° γ: 90°
R-values:
R R work R free
0.245 0.242 0.288
Expression systems:
  • Escherichia coli
  • Mus musculus