PDBe 4yoo

X-ray diffraction
2.4Å resolution

p107 pocket domain in complex with LIN52 P29A peptide

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Retinoblastoma-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 369 amino acids
Theoretical weight: 43.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: P28749 (Residues: 391-972; Coverage: 34%)
Gene name: RBL1
Sequence domains: Retinoblastoma-associated protein B domain
Structure domains: Cyclin-like
Protein lin-52 homolog Chain: X
Molecule details ›
Chain: X
Length: 20 amino acids
Theoretical weight: 2.36 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q52LA3 (Residues: 15-34; Coverage: 17%)
Gene names: C14orf46, LIN52

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: C2221
Unit cell:
a: 74.815Å b: 100.53Å c: 142.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.195 0.242
Expression systems:
  • Escherichia coli 'BL21-Gold(DE3)pLysS AG'
  • Not provided