4yho

X-ray diffraction
1.82Å resolution

Reversal Agent for Dabigatran

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
aDabi-Fab3 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.77 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
Structure domains: Immunoglobulins
aDabi-Fab3 light chain Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.12 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 60.278Å b: 78.089Å c: 93.372Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.21
Expression system: Cricetinae