X-ray diffraction
1.95Å resolution

Function and Biology Details

Reaction catalysed:
Fumitremorgin B + 2-oxoglutarate + 2 O(2) + AH(2) = verruculogen + succinate + CO(2) + H(2)O + A
Biochemical function:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Verruculogen synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 315 amino acids
Theoretical weight: 35.38 KDa
Source organism: Aspergillus fumigatus Af293
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
  • Canonical: Q4WAW9 (Residues: 2-291; Coverage: 100%)
Gene names: AFUA_8G00230, ftmF, ftmOx1
Sequence domains: Phytanoyl-CoA dioxygenase (PhyH)
Structure domains: q2cbj1_9rhob like domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P21
Unit cell:
a: 60.445Å b: 45.561Å c: 105.409Å
α: 90° β: 99.74° γ: 90°
R R work R free
0.166 0.164 0.204
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'