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Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA

Source organism: Homo sapiens
Biochemical function: RNA binding
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00076
Domain description: RNA recognition motif
Occurring in:
  1. TAR DNA-binding protein 43
The deposited structure of PDB entry 4y0f contains 2 copies of Pfam domain PF00076 (RNA recognition motif) in TAR DNA-binding protein 43. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000504
Domain description: RNA recognition motif domain
Occurring in:
  1. TAR DNA-binding protein 43
IPR035979
Domain description: RNA-binding domain superfamily
Occurring in:
  1. TAR DNA-binding protein 43
IPR012677
Domain description: Nucleotide-binding alpha-beta plait domain superfamily
Occurring in:
  1. TAR DNA-binding protein 43

Structure domain

CATH CATH domain
3.30.70.330
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Alpha-Beta Plaits
Occurring in:
  1. TAR DNA-binding protein 43
The deposited structure of PDB entry 4y0f contains 2 copies of CATH domain 3.30.70.330 (Alpha-Beta Plaits) in TAR DNA-binding protein 43. Showing 1 copy in chain A.

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