PDBe 4xoi

X-ray diffraction
2.09Å resolution

Structure of hsAnillin bound with RhoA(Q63L) at 2.1 Angstroms resolution

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transforming protein RhoA Chains: A, C
Molecule details ›
Chains: A, C
Length: 180 amino acids
Theoretical weight: 20.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61586 (Residues: 1-180; Coverage: 93%)
Gene names: ARH12, ARHA, RHO12, RHOA
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Anillin Chains: B, D
Molecule details ›
Chains: B, D
Length: 270 amino acids
Theoretical weight: 29.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NQW6 (Residues: 712-981; Coverage: 24%)
Gene name: ANLN
Sequence domains: Cell division protein anillin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P1
Unit cell:
a: 54.311Å b: 52.434Å c: 103.101Å
α: 77.87° β: 74.14° γ: 85.73°
R-values:
R R work R free
0.174 0.173 0.206
Expression system: Escherichia coli