4xih

X-ray diffraction
2.25Å resolution

Crystal structure of the R116A mutant AhpE from Mycobacterium tuberculosis

Released:

Function and Biology Details

Reaction catalysed:
Mycoredoxin + ROOH = mycoredoxin disulfide + H(2)O + ROH
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alkyl hydroperoxide reductase E Chains: A, B
Molecule details ›
Chains: A, B
Length: 153 amino acids
Theoretical weight: 16.81 KDa
Source organism: Mycobacterium tuberculosis CCDC5079
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WIE3 (Residues: 1-152; Coverage: 99%)
Gene names: MTCY427.19c, Rv2238c, ahpE
Sequence domains: AhpC/TSA family
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: I4
Unit cell:
a: 147.26Å b: 147.26Å c: 33.303Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.224
Expression system: Escherichia coli