› › Function and Biology

Crystal Structure of F222 form of E112A/H234A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium

Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Biochemical function: XMP 5'-nucleosidase activity
Biological process: not assigned
Cellular component: cytoplasm

Quick links

EC 3.6.1.11: Exopolyphosphatase

Reaction catalysed:
(Polyphosphate)(n) + H(2)O = (polyphosphate)(n-1) + phosphate
Systematic name:
Polyphosphate phosphohydrolase
Alternative Name(s):
  • Acid phosphoanhydride phosphohydrolase
  • Exopolypase
  • Gra-Pase
  • Metaphosphatase

EC 3.1.3.6: 3'-nucleotidase

Reaction catalysed:
A 3'-ribonucleotide + H(2)O = a ribonucleoside + phosphate
Systematic name:
3'-ribonucleotide phosphohydrolase
Alternative Name(s):
  • 3'-mononucleotidase
  • 3'-phosphatase
  • 3'-ribonucleotidase

EC 3.1.3.5: 5'-nucleotidase

Reaction catalysed:
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate
Systematic name:
5'-ribonucleotide phosphohydrolase
Alternative Name(s):
  • 5'-AMP nucleotidase
  • 5'-AMPase
  • 5'-adenylic phosphatase
  • 5'-mononucleotidase
  • AMP phosphatase
  • AMP phosphohydrolase
  • AMPase
  • Adenosine 5'-phosphatase
  • Adenosine monophosphatase
  • IMP 5'-nucleotidase
  • Snake venom 5'-nucleotidase
  • Thimidine monophosphate nucleotidase
  • UMPase
  • Uridine 5'-nucleotidase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01975
Domain description: Survival protein SurE
Occurring in:
  1. 5'/3'-nucleotidase SurE
The deposited structure of PDB entry 4xep contains 1 copy of Pfam domain PF01975 (Survival protein SurE) in 5'/3'-nucleotidase SurE. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002828
Domain description: Survival protein SurE-like phosphatase/nucleotidase
Occurring in:
  1. 5'/3'-nucleotidase SurE
IPR030048
Domain description: Survival protein SurE
Occurring in:
  1. 5'/3'-nucleotidase SurE
IPR036523
Domain description: SurE-like phosphatase/nucleotidase superfamily
Occurring in:
  1. 5'/3'-nucleotidase SurE

Structure domain

CATH CATH domain
3.40.1210.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Stationary-phase Survival Protein Sure Homolog; Chain: A,
Homology: Survival protein SurE-like phosphatase/nucleotidase
Occurring in:
  1. 5'/3'-nucleotidase SurE
The deposited structure of PDB entry 4xep contains 1 copy of CATH domain 3.40.1210.10 (Stationary-phase Survival Protein Sure Homolog; Chain: A,) in 5'/3'-nucleotidase SurE. Showing 1 copy in chain A.

Quick links