X-ray diffraction
1.5Å resolution

Crystal Structure of F222 form of E112A/H234A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium


Function and Biology Details

Reactions catalysed:
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate
A 3'-ribonucleotide + H(2)O = a ribonucleoside + phosphate
(Polyphosphate)(n) + H(2)O = (polyphosphate)(n-1) + phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
5'/3'-nucleotidase SurE Chain: A
Molecule details ›
Chain: A
Length: 267 amino acids
Theoretical weight: 28.49 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Expression system: Escherichia coli
  • Canonical: P66881 (Residues: 1-253; Coverage: 100%)
Gene names: STM2927, surE
Sequence domains: Survival protein SurE
Structure domains: Survival protein SurE-like phosphatase/nucleotidase

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: F222
Unit cell:
a: 73.455Å b: 121.653Å c: 143.401Å
α: 90° β: 90° γ: 90°
R R work R free
0.189 0.187 0.229
Expression system: Escherichia coli