Function and Biology Details
Reaction catalysed:
(2R)-2,3-dihydroxy-3-methylbutanoate + NAD(P)(+) = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Ketol-acid reductoisomerase (NAD(P)(+)) (preferred)
PDBe Complex ID:
PDB-CPX-122695 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ketol-acid reductoisomerase (NAD(P)(+))
Molecule details ›
Chains: A, B
Length: 343 amino acids
Theoretical weight: 38.47 KDa
Source organism: Ignisphaera aggregans DSM 17230
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 343 amino acids
Theoretical weight: 38.47 KDa
Source organism: Ignisphaera aggregans DSM 17230
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
E0SRA9 (Residues: 1-335; Coverage: 100%)
Sequence domains:
- Acetohydroxy acid isomeroreductase, NADPH-binding domain
- Acetohydroxy acid isomeroreductase, catalytic domain
