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METHYLTRANSFERASE DOMAIN OF SMALL RNA 2'-O-METHYLTRANSFERASE

X-ray diffraction
2.84Å resolution
PDB entry 4xcx coloured by chain, front view.
PDB entry 4xcx coloured by chain, side view.
PDB entry 4xcx coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Small RNA 2'-O-methyltransferase
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Multimeric state: monomeric
Accessible surface area: 10684.58 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-178312

Macromolecules

Small RNA 2'-O-methyltransferase
Chain: A
Length: 249 amino acids
Theoretical weight: 28.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5T8I9 (Residues: 14-262; Coverage: 63%)
Gene names: C1orf59, HENMT1
Pfam: Methyltransferase domain
InterPro:
CATH: Vaccinia Virus protein VP39
Small RNA 2'-O-methyltransferase in PDB entry 4xcx, assembly 1, front view.
Small RNA 2'-O-methyltransferase in PDB entry 4xcx, assembly 1, side view.
Small RNA 2'-O-methyltransferase in PDB entry 4xcx, assembly 1, top view.
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