› 4xch

X-ray diffraction
2.2Å resolution

S-ribosylhomocysteinase from Streptococcus suis

Released:
DOI: 10.2210/pdb4xch/pdb
PDB entry 4xch coloured by chain, front view.
PDB entry 4xch coloured by chain, side view.
PDB entry 4xch coloured by chain, top view.
Source organism: Streptococcus suis
Entry authors: Wang Y, Mao X, Lu C

Function and Biology Details

Reaction catalysed: 
S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109497 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
S-ribosylhomocysteine lyase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 194 amino acids
Theoretical weight: 21.57 KDa
Source organism: Streptococcus suis
Expression system: Escherichia coli
UniProt:
  • Canonical: B2CMA5 (Residues: 1-160; Coverage: 100%)
Gene names: BKM66_02135, CWI26_02315, DP112_02115, E8L09_03510, EI219_01695, EI220_02925, EI993_10195, ERS132356_01073, ERS132370_00961, ERS132374_01231, ERS132385_02012, ERS132389_01834, ERS132393_01644, ERS132394_02435, ERS132399_01689, ERS132406_01843, ERS132410_02026, ERS132414_02185, ERS132416_02052, ERS132417_01483, ERS132421_01978, ERS132426_01439, ERS132431_01162, ERS132442_01708, ERS132444_01395, ERS132452_02056, ERS132453_01003, ERS132457_01732, ERS132461_01882, ERS132462_01078, ERS132522_01194, ERS132536_01573, ERS132551_01663, ERS156295_01316, FAJ34_07790, FAJ35_04535, FH692_08165, FH693_08475, HO898_07100, HU146_05635, I5V48_09340, NOL11_05995, NOL13_10460, SSU1300283_00411, luxS
Sequence domains: S-Ribosylhomocysteinase (LuxS)
Structure domains: S-ribosylhomocysteinase (LuxS)

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 74.89Å b: 86.25Å c: 103.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.233
Expression system: Escherichia coli

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