X-ray diffraction
3.2Å resolution

Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains (with zinc)


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Down syndrome cell adhesion molecule 1, isoform AU Chains: A, B
Molecule details ›
Chains: A, B
Length: 396 amino acids
Theoretical weight: 43.41 KDa
Source organism: Drosophila melanogaster
Expression system: Trichoplusia ni
  • Canonical: Q0E9L5 (Residues: 34-427; Coverage: 20%)
Gene names: 43Bc, CG17800, CT39257, DSCAM, DScam, DmDscam, Dm_2R:13579, Dm_2R:13612, Dmel\CG17800, Dmel_CG17800, DsCam, Dscam, Dscam-hv, Dscam1, Dsm, Neu1, dScam, dscam, dscam1, l(2)05518, l(2)43Bc, p270
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P21
Unit cell:
a: 66.672Å b: 57.269Å c: 129.946Å
α: 90° β: 93.65° γ: 90°
R R work R free
0.256 0.253 0.316
Expression system: Trichoplusia ni