PDBe 4xb0

X-ray diffraction
2.7Å resolution

Structure of the Plk2 polo-box domain

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase PLK2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 218 amino acids
Theoretical weight: 25.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NYY3 (Residues: 468-685; Coverage: 32%)
Gene names: PLK2, SNK
Sequence domains: POLO box duplicated region
Structure domains: POLO box domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: I23
Unit cell:
a: 152.292Å b: 152.292Å c: 152.292Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.225 0.263
Expression system: Escherichia coli