› 4x9g

X-ray diffraction
3.4Å resolution

Crystal structure of Dscam1 isoform 6.44, N-terminal four Ig domains

Released:
DOI: 10.2210/pdb4x9g/pdb
PDB entry 4x9g coloured by chain, front view.
PDB entry 4x9g coloured by chain, side view.
PDB entry 4x9g coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition.
Li SA, Cheng L, Yu Y, Wang JH, Chen Q
Sci Adv 2 e1501118 (2016)
PMID: 27386517

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192416 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Cell adhesion molecule Dscam1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 394 amino acids
Theoretical weight: 43.15 KDa
Source organism: Drosophila melanogaster
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q0E9H9 (Residues: 34-268, 269-424; Coverage: 20%)
Gene names: CG17800, Dscam, Dscam1, p270
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: C2
Unit cell:
a: 193.639Å b: 63.416Å c: 90.073Å
α: 90° β: 99.94° γ: 90°
R-values:
R R work R free
0.252 0.248 0.317
Expression system: Trichoplusia ni

Quick links

Citations

2 review citations

Writing, Reading, and Translating the Clustered Protocadherin Cell Surface Recognition Code for Neural Circuit Assembly.
Mountoufaris et al. (2018)
1 more