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Immunoglobulin Fc heterodimers variant

X-ray diffraction
2.498Å resolution
PDB entry 4x99 coloured by chain, front view.
PDB entry 4x99 coloured by chain, side view.
PDB entry 4x99 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: IG-heavy chain
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Multimeric state: hetero dimer
Accessible surface area: 22458.58 Å2
Buried surface area: 6995.31 Å2
Dissociation area: 1,149.96 Å2
Dissociation energy (ΔGdiss): 4.54 kcal/mol
Dissociation entropy (TΔSdiss): 13.32 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-134813

Macromolecules

Immunoglobulin heavy constant gamma 1
Chain: A
Length: 223 amino acids
Theoretical weight: 25.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01857 (Residues: 108-328; Coverage: 55%)
Gene name: IGHG1
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
Immunoglobulin heavy constant gamma 1 in PDB entry 4x99, assembly 1, front view.
Immunoglobulin heavy constant gamma 1 in PDB entry 4x99, assembly 1, side view.
Immunoglobulin heavy constant gamma 1 in PDB entry 4x99, assembly 1, top view.
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Immunoglobulin heavy constant gamma 1
Chain: B
Length: 223 amino acids
Theoretical weight: 25.08 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01857 (Residues: 108-328; Coverage: 55%)
Gene name: IGHG1
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
Immunoglobulin heavy constant gamma 1 in PDB entry 4x99, assembly 1, front view.
Immunoglobulin heavy constant gamma 1 in PDB entry 4x99, assembly 1, side view.
Immunoglobulin heavy constant gamma 1 in PDB entry 4x99, assembly 1, top view.
Molecule details ›

Search similar proteins

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