Function and Biology

Crystal structure of Ash2L SPRY domain in complex with RbBP5

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: Set1C/COMPASS complex

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00622
Domain description: SPRY domain
Occurring in:
  1. Set1/Ash2 histone methyltransferase complex subunit ASH2
The deposited structure of PDB entry 4x8p contains 1 copy of Pfam domain PF00622 (SPRY domain) in Set1/Ash2 histone methyltransferase complex subunit ASH2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003877
Domain description: SPRY domain
Occurring in:
  1. Set1/Ash2 histone methyltransferase complex subunit ASH2
IPR013320
Domain description: Concanavalin A-like lectin/glucanase domain superfamily
Occurring in:
  1. Set1/Ash2 histone methyltransferase complex subunit ASH2
IPR037353
Domain description: Histone methyltransferase complex subunit ASH2
Occurring in:
  1. Set1/Ash2 histone methyltransferase complex subunit ASH2
IPR043136
Domain description: B30.2/SPRY domain superfamily
Occurring in:
  1. Set1/Ash2 histone methyltransferase complex subunit ASH2
IPR001870
Domain description: B30.2/SPRY domain
Occurring in:
  1. Set1/Ash2 histone methyltransferase complex subunit ASH2

Structure domain

CATH CATH domain
2.60.120.920
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. Set1/Ash2 histone methyltransferase complex subunit ASH2
The deposited structure of PDB entry 4x8p contains 1 copy of CATH domain 2.60.120.920 (Jelly Rolls) in Set1/Ash2 histone methyltransferase complex subunit ASH2. Showing 1 copy in chain A.