PDBe 4x6f

X-ray diffraction
1.91Å resolution

CD1a binary complex with sphingomyelin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T-cell surface glycoprotein CD1a Chain: A
Molecule details ›
Chain: A
Length: 281 amino acids
Theoretical weight: 32.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P06126 (Residues: 21-295; Coverage: 88%)
Gene name: CD1A
Sequence domains: Immunoglobulin C1-set domain
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 105 amino acids
Theoretical weight: 12.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 42.38Å b: 90.21Å c: 107.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.187 0.224
Expression system: Homo sapiens