PDBe 4x5o

X-ray diffraction
2.8Å resolution

Human histidine tRNA synthetase

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histidine--tRNA ligase, cytoplasmic Chains: A, B
Molecule details ›
Chains: A, B
Length: 509 amino acids
Theoretical weight: 57.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12081 (Residues: 1-509; Coverage: 100%)
Gene names: HARS, HRS
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P41212
Unit cell:
a: 97.669Å b: 97.669Å c: 254.409Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.252 0.248 0.314
Expression system: Escherichia coli