4x3h

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF ARC N-LOBE COMPLEXED WITH STARGAZIN PEPTIDE

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Activity-regulated cytoskeleton-associated protein Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 9.35 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q63053 (Residues: 207-277; Coverage: 18%)
Gene name: Arc
Voltage-dependent calcium channel gamma-2 subunit Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 1.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O88602 (Residues: 225-233; Coverage: 3%)
Gene names: Cacng2, Stg

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: P3221
Unit cell:
a: 54.317Å b: 54.317Å c: 69.555Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.211 0.244
Expression system: Escherichia coli BL21