EC 1.2.1.36: Retinal dehydrogenase
Reaction catalysed:
Retinal + NAD(+) + H(2)O = retinoate + NADH
Systematic name:
Retinal:NAD(+) oxidoreductase
Alternative Name(s):
- Cytosolic retinal dehydrogenase
GO terms
Biochemical function:
Biological process:
- regulation of vascular endothelial cell proliferation
- retinoic acid receptor signaling pathway involved in somitogenesis
- cellular response to retinoic acid
- face development
- protein homotetramerization
- cardiac muscle tissue development
- embryonic digestive tract development
- retinoic acid receptor signaling pathway
- positive regulation of apoptotic process
- camera-type eye development
- 9-cis-retinoic acid biosynthetic process
- retinal metabolic process
- retinoic acid metabolic process
- retinol metabolic process
- ureter maturation
- embryonic forelimb morphogenesis
- response to cytokine
- response to vitamin A
- response to retinoic acid
- response to estradiol
- embryonic camera-type eye development
- pancreas development
- hindbrain development
- forebrain development
- embryonic limb morphogenesis
- lung development
- neuron differentiation
- pituitary gland development
- neural tube development
- morphogenesis of embryonic epithelium
- neural crest cell development
- positive regulation of gene expression
- proximal/distal pattern formation
- anterior/posterior pattern specification
- determination of bilateral symmetry
- negative regulation of cell population proliferation
- positive regulation of cell population proliferation
- cell population proliferation
- midgut development
- vitamin A metabolic process
- lipid metabolic process
- heart morphogenesis
- retinoic acid biosynthetic process
- liver development
- kidney development
- blood vessel development
Cellular component:
Sequence family
Protein family (Pfam)
InterPro annotationsStructure domains
CATH domains
3.40.309.10
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Aldehyde Dehydrogenase; Chain A, domain 2
Homology:
Aldehyde Dehydrogenase; Chain A, domain 2
Occurring in:
