› 4wuk

X-ray diffraction
1.7Å resolution

Crystal structure of apo CH65 Fab

Released:
DOI: 10.2210/pdb4wuk/pdb
PDB 4wuk coloured by chain and viewed from the front.
PDB 4wuk coloured by chain and viewed from the side.
PDB 4wuk coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Lee PS, Wilson IA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CH65 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 235 amino acids
Theoretical weight: 25.41 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Structure domains: Immunoglobulins
CH65 light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 22.72 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NHE 2 x NHE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P212121
Unit cell:
a: 57.095Å b: 67.024Å c: 130.551Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.207
Expression system: Trichoplusia ni

Quick links

Citations

1 review citation

Structure-Based Vaccine Antigen Design.
Graham et al. (2019)
1 other article

3 mentions without citation

Members of the Hsp70 Family Recognize Distinct Types of Sequences to Execute ER Quality Control.
Behnke et al. (2016)
2 more