X-ray diffraction
1.9Å resolution

Function and Biology Details

Reactions catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Endolysin; Phosphatidylinositol 4-kinase type 2-beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 514 amino acids
Theoretical weight: 59.37 KDa
Source organisms: Expression system: Escherichia coli BL21
  • Canonical: P00720 (Residues: 2-164; Coverage: 99%)
  • Canonical: Q8TCG2 (Residues: 90-165, 176-450; Coverage: 73%)
Gene names: E, PI4K2B
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P41212
Unit cell:
a: 106.01Å b: 106.01Å c: 214.53Å
α: 90° β: 90° γ: 90°
R R work R free
0.21 0.209 0.24
Expression system: Escherichia coli BL21