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The crystal structure of hemagglutinin form A/chicken/New York/14677-13/1998 in complex with LSTa

X-ray diffraction
2.8Å resolution
PDB entry 4wss coloured by chain, front view.
PDB entry 4wss coloured by chain, side view.
PDB entry 4wss coloured by chain, top view.
Source organism: Influenza A virus (A/chicken/New York/14677-13/1998(H6N2))
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1
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Assembly Name: Hemagglutinin HA2 chain
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Multimeric state: homo trimer
Accessible surface area: 60221.18 Å2
Buried surface area: 14157.97 Å2
Dissociation area: 5,953.79 Å2
Dissociation energy (ΔGdiss): 39.67 kcal/mol
Dissociation entropy (TΔSdiss): 31.93 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-170844
Assembly 2 (preferred)
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Assembly Name: Hemagglutinin HA2 chain
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Multimeric state: homo trimer
Accessible surface area: 61727.65 Å2
Buried surface area: 14492.37 Å2
Dissociation area: 5,840.18 Å2
Dissociation energy (ΔGdiss): 32.88 kcal/mol
Dissociation entropy (TΔSdiss): 31.94 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-170844

Macromolecules

Hemagglutinin HA2 chain
Chains: A, B, C, D, E, F
Length: 514 amino acids
Theoretical weight: 57.87 KDa
Source organism: Influenza A virus (A/chicken/New York/14677-13/1998(H6N2))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q0A3A5 (Residues: 17-522; Coverage: 89%)
Gene name: HA
Pfam: Haemagglutinin
InterPro:
CATH:
Hemagglutinin HA2 chain in PDB entry 4wss, assembly 2, front view.
Hemagglutinin HA2 chain in PDB entry 4wss, assembly 2, side view.
Hemagglutinin HA2 chain in PDB entry 4wss, assembly 2, top view.
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