Assemblies
Multimeric state:
hetero hexamer
Accessible surface area:
136944.16 Å2
Buried surface area:
34730.89 Å2
Dissociation area:
3,631.16
Å2
Dissociation energy (ΔGdiss):
9
kcal/mol
Dissociation entropy (TΔSdiss):
16.23
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-233040
Multimeric state:
hetero hexamer
Accessible surface area:
135023.1 Å2
Buried surface area:
35035.33 Å2
Dissociation area:
3,587.04
Å2
Dissociation energy (ΔGdiss):
6.06
kcal/mol
Dissociation entropy (TΔSdiss):
15.84
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-233040
Multimeric state:
hetero hexamer
Accessible surface area:
134517.71 Å2
Buried surface area:
34839.64 Å2
Dissociation area:
1,973.37
Å2
Dissociation energy (ΔGdiss):
-1.88
kcal/mol
Dissociation entropy (TΔSdiss):
13.82
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-233040
Macromolecules
Chains: A, B, F, G, K, L
Length: 315 amino acids
Theoretical weight: 35.06 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Pfam:
Length: 315 amino acids
Theoretical weight: 35.06 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q5SHR6 (Residues: 1-315; Coverage: 100%)
Pfam:
- RNA polymerase Rpb3/Rpb11 dimerisation domain
- RNA polymerase Rpb3/RpoA insert domain
- Bacterial RNA polymerase, alpha chain C terminal domain
Chains: C, H, M
Length: 1119 amino acids
Theoretical weight: 125.44 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Pfam:
Length: 1119 amino acids
Theoretical weight: 125.44 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q8RQE9 (Residues: 1-1119; Coverage: 100%)
Pfam:
- RNA polymerase beta subunit
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 3
- RNA polymerase beta subunit external 1 domain
- RNA polymerase Rpb2, domain 6
- RNA polymerase Rpb2, domain 7
- DNA-directed RNA polymerase beta subunit, bacterial-type
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
- RNA polymerase, beta subunit, protrusion
- DNA-directed RNA polymerase, subunit 2
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 2 superfamily
- RNA polymerase Rpb2, domain 3
- DNA-directed RNA polymerase, beta subunit, external 1 domain
- DNA-directed RNA polymerase, beta subunit, external 1 domain superfamily
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
- RNA polymerase Rpb2, OB-fold
- RNA polymerase, beta subunit, conserved site
- RNA polymerase Rpb2, domain 7
Chains: D, I, N
Length: 1524 amino acids
Theoretical weight: 171 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Pfam:
Length: 1524 amino acids
Theoretical weight: 171 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q8RQE8 (Residues: 1-1524; Coverage: 100%)
Pfam:
- RNA polymerase Rpb1, domain 1
- DNA-directed RNA polymerase subunit beta', hybrid domain
- RNA polymerase Rpb1, domain 2
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
- DNA-directed RNA polymerase, subunit beta-prime, bacterial type
- RNA polymerase Rpb1, clamp domain superfamily
- RNA polymerase Rpb1, domain 1
- DNA-directed RNA polymerase, subunit beta-prime
- RNA polymerase, N-terminal
- RNA polymerase, alpha subunit
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 3 superfamily
- RNA polymerase Rpb1, funnel domain superfamily
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
Chains: E, J, O
Length: 99 amino acids
Theoretical weight: 11.53 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Pfam: RNA polymerase Rpb6
InterPro:
Length: 99 amino acids
Theoretical weight: 11.53 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q8RQE7 (Residues: 1-99; Coverage: 100%)
Pfam: RNA polymerase Rpb6
InterPro:
Chains: X, Y, Z
Length: 156 amino acids
Theoretical weight: 17.34 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 156 amino acids
Theoretical weight: 17.34 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q5SJG6 (Residues: 1-28, 63-156; Coverage: 78%)
- Canonical: Q5SKM1 (Residues: 30-63; Coverage: 22%) nullnull
Pfam:
InterPro:
- Transcription elongation factor GreA/GreB family
- Transcription elongation factor, GreA/GreB, N-terminal domain superfamily
- Transcription elongation factor GreA/GreB
- Transcription elongation factor, GreA/GreB, N-terminal
- Transcription elongation factor GreA/GreB, C-terminal domain superfamily
- Transcription elongation factor, GreA/GreB, C-terminal
- Transcription elongation factor, GreA/GreB, conserved site