4wol

X-ray diffraction
1.77Å resolution

Crystal Structure of the DAP12 transmembrane domain in lipidic cubic phase

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TYRO protein tyrosine kinase-binding protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 33 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43914 (Residues: 35-67; Coverage: 36%)
Gene names: DAP12, KARAP, TYROBP

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 20.775Å b: 35.709Å c: 101.07Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.183 0.223
Expression system: Escherichia coli