› 4wnx

X-ray diffraction
2.72Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191600 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Netrin-4 Chain: A
Molecule details ›
Chain: A
Length: 433 amino acids
Theoretical weight: 48.15 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9JI33 (Residues: 30-462; Coverage: 71%)
Gene name: Ntn4
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand NAG 2 x NAG
Ligand CA 1 x CA
Ligand TAM 1 x TAM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 107.755Å b: 75.049Å c: 74.672Å
α: 90° β: 96.07° γ: 90°
R-values:
R R work R free
0.222 0.22 0.263
Expression system: Homo sapiens

Quick links

Citations

9 review citations

Complexities of the glomerular basement membrane.
Naylor et al. (2021)
8 more

4 mentions without citation

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.
Reuten et al. (2016)
3 more