X-ray diffraction
2.42Å resolution

Crystal Structure of Bovine G Protein Coupled-Receptor Kinase 5 in Complex with CCG215022


Function and Biology Details

Reaction catalysed:
ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
G protein-coupled receptor kinase 5 Chain: A
Molecule details ›
Chain: A
Length: 598 amino acids
Theoretical weight: 69.04 KDa
Source organism: Bos taurus
Expression system: Trichoplusia ni
  • Canonical: P43249 (Residues: 1-590; Coverage: 100%)
Gene names: GPRK5, GRK5
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P212121
Unit cell:
a: 48.106Å b: 70.104Å c: 182.825Å
α: 90° β: 90° γ: 90°
R R work R free
0.196 0.194 0.243
Expression system: Trichoplusia ni