4wnb

X-ray diffraction
1.76Å resolution

Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis bound to 3-OPC-CoA

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hydratase ChsH2 Chain: A
Molecule details ›
Chain: A
Length: 187 amino acids
Theoretical weight: 20.21 KDa
Source organism: Mycobacterium tuberculosis KZN 4207
Expression system: Escherichia coli
Structure domains: Hotdog Thioesterase
Hydratase ChsH1 Chain: B
Molecule details ›
Chain: B
Length: 129 amino acids
Theoretical weight: 13.97 KDa
Source organism: Mycobacterium tuberculosis C
Expression system: Escherichia coli
Structure domains: Hotdog Thioesterase

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P6122
Unit cell:
a: 51.882Å b: 51.882Å c: 436.235Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.216 0.255
Expression system: Escherichia coli