› 4wmy

X-ray diffraction
1.6Å resolution

Structure of Human intelectin-1 in complex with allyl-beta-galactofuranose

Released:
DOI: 10.2210/pdb4wmy/pdb
PDB 4wmy coloured by chain and viewed from the front.
PDB 4wmy coloured by chain and viewed from the side.
PDB 4wmy coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Wangkanont K, Kiessling LL, Forest KT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Intelectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 306 amino acids
Theoretical weight: 34.26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8WWA0 (Residues: 29-313; Coverage: 97%)
Gene names: INTL, ITLN, ITLN1, LFR, UNQ640/PRO1270

Ligands and Environments

2 bound ligands:
Ligand CA 6 x CA
Ligand 3S6 2 x 3S6
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P213
Unit cell:
a: 117.865Å b: 117.865Å c: 117.865Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.155 0.18
Expression system: Homo sapiens

Quick links

Citations

19 review citations

Sweet impersonators: Molecular mimicry of host glycans by bacteria.
de Jong et al. (2022)
18 more

1 mention without citation

Recognition of microbial glycans by soluble human lectins.
Wesener et al. (2017)