X-ray diffraction
1.61Å resolution

Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP

Entry authors: Kim HL, Sacchettini JC

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Phosphoenolpyruvate carboxykinase [GTP] Chain: A
Molecule details ›
Chain: A
Length: 622 amino acids
Theoretical weight: 69.05 KDa
Source organism: Mycobacterium tuberculosis H37Ra
Expression system: Escherichia coli BL21(DE3)
  • Canonical: A5TYT6 (Residues: 1-606; Coverage: 100%)
Gene names: MRA_0219, pckG
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: C2
Unit cell:
a: 105.616Å b: 123.009Å c: 64.035Å
α: 90° β: 116.97° γ: 90°
R R work R free
0.161 0.16 0.18
Expression system: Escherichia coli BL21(DE3)