4wip

X-ray diffraction
2.69Å resolution

DIX domain of human Dvl2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Segment polarity protein dishevelled homolog DVL-2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 97 amino acids
Theoretical weight: 10.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O14641 (Residues: 11-106; Coverage: 13%)
Gene name: DVL2
Sequence domains: DIX domain
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 56.3Å b: 84.82Å c: 98.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.222 0.248
Expression system: Escherichia coli BL21(DE3)