4wio

X-ray diffraction
3.15Å resolution

Crystal structure of the C89A GMP synthetase inactive mutant from Plasmodium falciparum in complex with glutamine

Released:

Function and Biology Details

Reaction catalysed:
(1a) L-glutamine + H(2)O = L-glutamate + NH(4)(+)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamine amidotransferase Chain: A
Molecule details ›
Chain: A
Length: 567 amino acids
Theoretical weight: 65.31 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IJR9 (Residues: 2-555; Coverage: 100%)
Gene name: PF3D7_1012600
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P43212
Unit cell:
a: 76.92Å b: 76.92Å c: 204.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.265 0.263 0.306
Expression system: Escherichia coli