› 4wel

X-ray diffraction
1.99Å resolution

Crystal structure of Pseudomonas aeruginosa PBP3 with SMC-3176

Released:
DOI: 10.2210/pdb4wel/pdb
PDB 4wel coloured by chain and viewed from the front.
PDB 4wel coloured by chain and viewed from the side.
PDB 4wel coloured by chain and viewed from the top.
Source organism: Pseudomonas aeruginosa PA14
Entry author: Ferguson AD

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Penicillin-binding protein 3 Chain: A
Molecule details ›
Chain: A
Length: 538 amino acids
Theoretical weight: 58.33 KDa
Source organism: Pseudomonas aeruginosa PA14
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0M3KKZ3 (Residues: 1-490; Coverage: 100%)
Gene name: CIA_00399
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand 3LE 1 x 3LE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 68.442Å b: 83.337Å c: 89.411Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.19 0.22
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials.
Sauvage et al. (2016)
3 more