4we5

X-ray diffraction
2.1Å resolution

The crystal structure of hemagglutinin from A/Port Chalmers/1/1973 influenza virus

Released:
Entry authors: Yang H, Carney PJ, Chang JC, Guo Z, Villanueva JM, Stevens J

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin HA1 chain Chain: A
Molecule details ›
Chain: A
Length: 328 amino acids
Theoretical weight: 36.13 KDa
Source organism: Influenza A virus (A/Port Chalmers/1/1973(H3N2))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q1PUD9 (Residues: 18-345; Coverage: 60%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Hemagglutinin HA2 chain Chain: B
Molecule details ›
Chain: B
Length: 181 amino acids
Theoretical weight: 20.84 KDa
Source organism: Influenza A virus (A/Port Chalmers/1/1973(H3N2))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q1PUD9 (Residues: 346-519; Coverage: 32%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: I213
Unit cell:
a: 153.128Å b: 153.128Å c: 153.128Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.231
Expression system: Trichoplusia ni