Structure analysis

Cytoplasmically Produced Homodimeric Single Domain Antibody (sdAb) C22A/C99V variant against Staphylococcal enterotoxin B (SEB)

X-ray diffraction
2Å resolution
Source organism: Lama glama
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 11909.68 Å2
Buried surface area: 1987.59 Å2
Dissociation area: 894.23 Å2
Dissociation energy (ΔGdiss): -7.24 kcal/mol
Dissociation entropy (TΔSdiss): 11.54 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-230418

Macromolecules

Chains: A, B
Length: 133 amino acids
Theoretical weight: 14.35 KDa
Source organism: Lama glama
Expression system: Escherichia coli BL21(DE3)
InterPro:
CATH: Immunoglobulins

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